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S4: Motion Correction

Volume-to-volume realignment for spinal cord fMRI.

Purpose

S4 corrects for subject motion during the functional acquisition using cord-optimized registration.

Algorithm

  1. Reference Volume Selection - Use robust reference from S3
  2. Iterative Registration - Register each volume to reference
  3. Motion Parameter Extraction - Extract 6 DOF parameters
  4. Outlier Detection - Flag high-motion volumes
  5. Interpolation - Apply transforms with sinc interpolation

Key Features

  • Cord-centric cost function
  • Regularized transforms for spinal cord geometry
  • Frame-wise displacement calculation
  • Integration with confound regression

Implementation in progress